James L. Spears, M.D.

Education & Training


Lankenau Hospital


Georgetown University Hospital


Georgetown University Hospital

Medical School

Case Western Reserve University School of Medicine

Board Certification


To schedule an appointment with this physician, please contact his office at 215-453-3300.

Penn Cancer Network Affiliate Practice Member

Office Contact Info:

Phone: (215) 453-3300

Specializes In:

Hospital Affiliations:

Philadelphia Magazine's Top Docs 2022James L. Spears, M.D. is a board-certified oncologist and hematologist with extensive experience in the diagnosis and treatment of every kind of cancer. He believes in comprehensive cancer care of the patient and their needs as a person, rather than only focusing on their illness.

Dr. Spears is an active member of the American Society of Clinical Oncology and American Medical Association.

Dr. James Spears has been chosen by his peers in the 2020 and 2021 Philadelphia Magazine’s Top Doc List. The list includes the Philadelphia region’s best physicians.

“I don’t believe I could have found a better doctor. Dr Spears is very smart, kind and caring. He explains everything thoroughly. Thanks Dr. Spears, you're an A+ doctor!”

- A Grateful Patient